The inflammatory process of ankylosing spondylitis (AS) can lead to fatigue. Though there is currently no cure for AS, there are steps you can take to help alleviate fatigue.

AS can cause pain, discomfort, and fatigue, which may disrupt daily activities. According to the National Ankylosing Spondylitis Society, fatigue is one of the most common concerns among people with AS.

The biggest cause of AS-related fatigue is inflamed tissues within the spine, which release small, protein-based chemicals called cytokines. Experts believe cytokines play a major role in fatigue, pain, and psychological disturbances.

Cytokines react in your body similarly to proteins your immune system produces when you have a cold or flu. This is why you may sometimes feel like you have a viral illness with AS when you don’t.

Treating inflammation with medications can help reduce excessive fatigue. But, keep in mind that prescription drugs that contain opioids or codeine may increase tiredness and they won’t decrease inflammation. Read on for some tips on how to manage AS fatigue.

In some cases, fatigue isn’t exclusively related to inflammation.

Pain and discomfort can make it difficult to fall asleep at night, worsening fatigue. Pain may also cause you to wake up during the night.

Doing the following may help you get a more restful night’s sleep:

  • going to bed at the same time every night, including during weekends
  • taking breaks from activity or work throughout the day instead of having naps
  • doing relaxing activities, such as deep breathing exercises or a warm bath, before bed
  • adding thicker curtains in your bedroom so the sunlight is less likely to wake you
  • regulating the temperature in your bedroom

Inflammation from AS increases your risk of anemia, a condition that involves a lack of healthy red blood cells. These cells are responsible for transporting oxygen to organs.

Fatigue is one of the first signs of anemia. Other anemia symptoms include:

Doctors diagnose anemia with a blood test. If you receive a diagnosis of anemia, your doctor may prescribe an iron supplement to help restore your red blood cell levels.

Your doctor will also want to make sure you don’t have ulcers or bleeding from nonsteroidal anti-inflammatory medication use or heavy menstrual periods.

A lack of energy can lead to decreased physical activity and weight gain. Having overweight can cause long-term health concerns and may make AS symptoms worse.

Carrying extra fat adds more stress to your spine and worsens inflammation. Overweight can also make everyday tasks more difficult to complete.

If you notice you’re gaining weight despite eating a healthy, balanced diet and exercising regularly, talk with your doctor. They may order additional tests, such as thyroid function tests, to determine the cause.

Unintended weight gain often calls for dietary adjustments. But, when it comes to addressing AS-related fatigue, it’s important to make specific changes. For example, eating nutrient-dense foods as often as possible will help keep your energy high all day.

It may be best to fill up on whole grains and carbs derived from produce rather than foods that contain a lot of sugar or refined flours. Also, you can try swapping caffeinated beverages for water.

When you’re feeling run down, working out is likely the furthest thing from your mind. Still, regular workouts can help improve energy levels and flexibility over time.

Exercise also helps keep your bones strong. This is important for people with AS, who are at an increased risk of developing osteoporosis later in life.

You might start with short walks and work your way up to longer, high intensity exercises. Swimming is a great exercise for people with AS.

You may also find it easier to fall asleep at night if you’ve worked out during day. Just try not to exercise too late in the evening, as doing so can disrupt your sleep.

Although there’s currently no cure for AS, you can take steps to help you manage the condition’s symptoms.

If you find you often don’t have enough energy to perform daily activities, it may be best to review and evaluate your current treatment plan with your doctor. A different approach may help keep fatigue at bay.

Try to remain positive and calm, as stress can add to feelings of tiredness. So, cut yourself some slack as you aim for more rest.