Inject Repatha only on the day of your scheduled dose, not a day early. But you may be able to shift your usual injection time of day.
Repatha (evolocumab) is a prescription biologic drug. Doctors may prescribe Repatha for high cholesterol or to reduce some risks if you have heart disease. Sometimes, they prescribe other medications with Repatha, such as statins, which are drugs that can help lower cholesterol.
Repatha has received Food and Drug Administration (FDA) approval for use in adults and some children ages 10 years and older. Typically, you inject Repatha once every 2 weeks or once monthly.
This article gives you a brief overview of the usual doses and the dosing schedule.
Do not inject Repatha earlier than your scheduled injection day, even when traveling. This instruction applies to any dose, including injections of 140 milligrams (mg) or 420 mg. The drugmaker doesn’t provide recommendations for injecting Repatha doses early.
The dosing details for Repatha depend on the medical condition you take the drug to treat. They involve either of the following dosages:
- 140 milligrams (mg) once every 2 weeks
- 420 mg once monthly
Your doctor will prescribe the best dose of Repatha for you. They’ll also instruct you on how often to inject your dose. Always follow your doctor’s dosage instructions.
Inject Repatha only at the intervals your doctor prescribes. If you inject Repatha more often than your doctor prescribes, you may have side effects or overdose symptoms.
If you inject more than the recommended amount of Repatha, call your doctor right away or get emergency medical attention. You can also call 800-222-1222 to reach America’s Poison Centers or use its online resource.
You can inject Repatha at any time of the day that’s convenient for you. Repatha isn’t known to
Choose a time of day that fits into your schedule and one that you’ll likely remember.
If needed, you can shift from your usual dosing time on your scheduled dosing day.
If you miss a Repatha injection, when you inject your next dose depends on your missed dose’s due date:
- If it’s been fewer than 7 days since your missed dose’s due date: Inject your next dose as soon as possible.
- If it’s been more than 7 days since your missed dose’s due date:
- For doses scheduled once every 2 weeks: Skip the missed dose. Then, inject the next dose based on your original schedule.
- For doses scheduled once monthly: Inject the missed dose. Then, start a new schedule based on this date.
If you’re not sure when to inject Repatha after a late dose, ask your doctor or pharmacist.
Do not inject Repatha earlier than your scheduled dosage day, such as a day or two early. Your doctor will instruct you on how and when to inject Repatha.
Typically, you’ll inject Repatha once every 2 weeks or once monthly. Injecting Repatha more often than prescribed may cause you to have side effects or overdose symptoms.
You can inject Repatha at any time of the day, with or without meals. If needed, you can shift from your usual dosing time on a scheduled dosing day. This shift in time may be more convenient during travel.
Follow your doctor’s instructions if you miss a dose of Repatha. These instructions depend on which dosage schedule of Repatha they have prescribed you.
Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.